Safety profile of grepafloxacin compared with other fluoroquinolones
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چکیده
منابع مشابه
Safety profile of the respiratory fluoroquinolone moxifloxacin: comparison with other fluoroquinolones and other antibacterial classes.
Moxifloxacin, a fluoroquinolone with potent activity against respiratory pathogens, is approved and considered as an alternative to beta-lactams and macrolides for the treatment of acute bacterial sinusitis and lower respiratory tract infections. In this review, we critically examine its safety profile in comparison with other fluoroquinolones and other antibacterial classes sharing similar ind...
متن کاملClinical Safety Profile of Fluoroquinolones
Introduction Fluoroquinolones have demonstrated comparable efficacy and rates of adverse events as β-lactam and/or macrolide agents in the treatment of community-acquired and healthcare-associated infections. Fluoroquinolones currently marketed are generally considered to have good safety profiles (1–5). However, post-marketing spontaneous adverse event reports have imposed updates in the preca...
متن کاملAntipneumococcal activity of grepafloxacin compared to that of other agents by time-kill methodology.
Time-kill studies compared the activities of grepafloxacin with those of ciprofloxacin, levofloxacin, sparfloxacin, amoxicillin-clavulanate, and clarithromycin against 12 pneumococcal strains. Grepafloxacin was bactericidal after 24 h against all strains at a concentration of < or = 0.5 microg/ml, while sparfloxacin, levofloxacin, and ciprofloxacin were bactericidal at concentrations of < or = ...
متن کاملThe relative safety of ephedra compared with other herbal products.
BACKGROUND Ephedra is widely used in dietary supplements that are marketed to promote weight loss or increase energy; however, the safety of this product has been questioned because of numerous case reports of adverse events. OBJECTIVE To compare the risk for adverse events attributable to ephedra and other herbal products. DESIGN Comparative case series. SETTING American Association of P...
متن کاملSafety of fluoroquinolones: An update.
The fluoroquinolone class of antimicrobials has been in clinical use for over 13 years. During that period, some representatives of the class have been extensively prescribed, such as ciprofloxacin and levofloxacin, while others have seen minimal use and have been restricted or withdrawn, namely, trovafloxacin and grepafloxacin. Manipulation of the fluoroquinolone structure by substituting a ra...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 1997
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/40.suppl_1.83